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Effects of Nitinol surface treatments and Ethylene oxide sterilization on human lymphocyte proliferation

S. Shabalovskayal and J. Anderegg; Institute for Physical Research and Technology, Ames Laboratory, Ames, IA; J. Wataha, Medical College of Georgia School of Dentistry, Augusta, GA; P. Poncet. Memry Corporation, Bethel CT; J. Cunnick, Dept. of Animal Science, Iowa State University, Ames IA. Published in Journal Biomedical Materials Research, 2003.

Surface treatment and sterilization are those critical protocols in the manufacturing of implant devices that can eventually predetermine the outcome of implantation. Biological performance of well characterized Nitinol surfaces (mechanically polished, chemically etched, aged in boiling water, heat treated, and electropolished) was evaluated using human peripheral blood lymphocyte proliferation test…. Download the entire paper.